Toby J. Athersuch: search on Z-Library

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1

Isotopic enrichment enhancement in metabonomic analysis of UPLC–MS data sets

Toby J. Athersuch, Jeremy K. Nicholson, Ian D. Wilson

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2007

Language:

english

File:

PDF, 102 KB

english, 2007

2

Robust Algorithms for Automated Chemical Shift Calibration of 1D 1H NMR Spectra of Blood Serum

Pearce, Jake T. M., Athersuch, Toby J., Ebbels, Timothy M. D., Lindon, John C., Nicholson, Jeremy K., Keun, Hector C.

Journal:

Analytical Chemistry

Year:

2008

Language:

english

File:

PDF, 1.11 MB

english, 2008

3

Heteronuclear 19 F− 1 H Statistical Total Correlation Spectroscopy as a Tool in Drug Metabolism: Study of Flucloxacillin Biotransformation

Keun, Hector C., Athersuch, Toby J., Beckonert, Olaf, Wang, Yulan, Saric, Jasmina, Shockcor, John P., Lindon, John C., Wilson, Ian D., Holmes, Elaine, Nicholson, Jeremy K.

Journal:

Analytical Chemistry

Year:

2008

Language:

english

File:

PDF, 457 KB

english, 2008

4

Two electron reduction of 2,3-dimethoxy-1,4-naphthoquinone metabolism in vivo prevents redox stress but interaction with the electron transport chain may be a mechanism of toxicity

Timothy Gant, Ursula Lutz, Joel Parry, Amy Pointon, Joanne Charlwood, Friederike Teichert, Toby Athersuch, Emma Taylor, Hector Keun, Jonathan Lyon, Werner Lutz

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 67 KB

english, 2009

5

Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population

James K Ellis, Toby J Athersuch, Laura DK Thomas, Friederike Teichert, Miriam Pérez-Trujillo, Claus Svendsen, David J Spurgeon, Rajinder Singh, Lars Järup, Jacob G Bundy, Hector C Keun

Journal:

Year:

2012

Language:

english

File:

PDF, 2.41 MB

english, 2012

6

Development of quantitative structure-metabolism (QSMR) relationships for substituted anilines based on computational chemistry

Athersuch, Toby J., Wilson, Ian D., Keun, Hector C., Lindon, John C.

Journal:

Year:

2013

Language:

english

File:

PDF, 476 KB

english, 2013

7

Chiral Metabonomics: 1 H NMR-Based Enantiospecific Differentiation of Metabolites in Human Urine via Direct Cosolvation with β-Cyclodextrin

Pérez-Trujillo, Míriam, Lindon, John C., Parella, Teodor, Keun, Hector C., Nicholson, Jeremy K., Athersuch, Toby J.

Journal:

Analytical Chemistry

Year:

2012

Language:

english

File:

PDF, 1.54 MB

english, 2012

8

A Combination of Transcriptomics and Metabolomics Uncovers Enhanced Bile Acid Biosynthesis in HepG2 Cells Expressing CCAAT/Enhancer-Binding Protein β (C/EBPβ), Hepatocyte Nuclear Factor 4α (HNF4α), and Constitutive Androstane Receptor (CAR)

Blazquez, Marina, Carretero, Aitor, Ellis, James K., Athersuch, Toby J., Cavill, Rachel, Ebbels, Timothy M. D., Keun, Hector C., Castell, José V., Lahoz, Agustín, Bort, Roque

Journal:

Journal of Proteome Research

Year:

2013

Language:

english

File:

PDF, 2.04 MB

english, 2013

9

Evaluation of 1 H NMR Metabolic Profiling Using Biofluid Mixture Design

Athersuch, Toby J., Malik, Shahid, Weljie, Aalim, Newton, Jack, Keun, Hector C.

Journal:

Analytical Chemistry

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

10

Effect of the Histone Deacetylase Inhibitor Trichostatin A on the Metabolome of Cultured Primary Hepatocytes

Ellis, James K., Chan, Pui Hei, Doktorova, Tatyana, Athersuch, Toby J., Cavill, Rachel, Vanhaecke, Tamara, Rogiers, Vera, Vinken, Mathieu, Nicholson, Jeremy K., M. D. Ebbels, Timothy, Keun, Hector C.

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 1.55 MB

english, 2010

11

Kinetic and J -Resolved Statistical Total Correlation NMR Spectroscopy Approaches to Structural Information Recovery in Complex Reacting Mixtures: Application to Acyl Glucuronide Intramolecular Transacylation Reactions

Johnson, Caroline H., Athersuch, Toby J., Wilson, Ian D., Iddon, Lisa, Meng, Xiaoli, Stachulski, Andrew V., Lindon, John C., Nicholson, Jeremy K.

Journal:

Analytical Chemistry

Year:

2008

Language:

english

File:

PDF, 1.16 MB

english, 2008

12

Pivotal Role for Two Electron Reduction in 2,3-Dimethoxy-1,4-naphthoquinone and 2-Methyl-1,4-naphthoquinone Metabolism and Kinetics in Vivo That Prevents Liver Redox Stress

Parry, Joel D., Pointon, Amy V., Lutz, Ursula, Teichert, Friederike, Charlwood, Joanne K., Chan, Pui Hei, Athersuch, Toby J., Taylor, Emma L., Singh, Rajinder, Luo, JinLi, Phillips, Kate M., Vetillard

Journal:

Chemical Research in Toxicology

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

13

Advancing the application of omics-based biomarkers in environmental epidemiology

Vineis, Paolo, van Veldhoven, Karin, Chadeau-Hyam, Marc, Athersuch, Toby J.

Journal:

Environmental and Molecular Mutagenesis

Year:

2013

Language:

english

File:

PDF, 121 KB

english, 2013

14

Meeting-in-the-middle using metabolic profiling – a strategy for the identification of intermediate biomarkers in cohort studies

Chadeau-Hyam, Marc, Athersuch, Toby J., Keun, Hector C., De Iorio, Maria, Ebbels, Timothy M.D., Jenab, Mazda, Sacerdote, Carlotta, Bruce, Stephen J, Holmes, Elaine, Vineis, Paolo

Journal:

Year:

2011

Language:

english

File:

PDF, 736 KB

english, 2011

15

Application of metabonomics in drug development

Keun, Hector C, Athersuch, Toby J

Journal:

Pharmacogenomics

Year:

2007

Language:

english

File:

PDF, 359 KB

english, 2007

16

Urinary metabolic profiles in early pregnancy are associated with preterm birth and fetal growth restriction in the Rhea mother–child cohort study

Maitre, Léa, Fthenou, Eleni, Athersuch, Toby, Coen, Muireann, Toledano, Mireille B, Holmes, Elaine, Kogevinas, Manolis, Chatzi, Leda, Keun, Hector C

Journal:

Year:

2014

Language:

english

File:

PDF, 775 KB

english, 2014

17

The role of metabolomics in characterizing the human exposome

Athersuch, Toby J

Journal:

Year:

2012

Language:

english

File:

PDF, 898 KB

english, 2012

18

The Human Early-Life Exposome (HELIX): Project Rationale and Design

Vrijheid, Martine, Slama, Rémy, Robinson, Oliver, Chatzi, Leda, Coen, Muireann, van den Hazel, Peter, Thomsen, Cathrine, Wright, John, Athersuch, Toby James, Avellana, Narcis, Basagaña, Xavier, Brocho

Journal:

Environmental Health Perspectives

Year:

2014

Language:

english

File:

PDF, 569 KB

english, 2014

19

Consensus-Phenotype Integration of Transcriptomic and Metabolomic Data Implies a Role for Metabolism in the Chemosensitivity of Tumour Cells

Cavill, Rachel, Kamburov, Atanas, Ellis, James K., Athersuch, Toby J., Blagrove, Marcus S. C., Herwig, Ralf, Ebbels, Timothy M. D., Keun, Hector C., Tucker-Kellogg, Greg

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 2.12 MB

english, 2011

20

Performance in Omics Analyses of Blood Samples in Long-Term Storage: Opportunities for the Exploitation of Existing Biobanks in Environmental Health Research

Hebels, Dennie G.A.J., Georgiadis, Panagiotis, Keun, Hector C., Athersuch, Toby J., Vineis, Paolo, Vermeulen, Roel, Portengen, Lutzen, Bergdahl, Ingvar A., Hallmans, Göran, Palli, Domenico, Bendinelli

Journal:

Environmental Health Perspectives

Year:

2013

Language:

english

File:

PDF, 3.84 MB

english, 2013

21

Metabolic profiling in human exposome studies

Athersuch, Toby J., Keun, Hector C.

Journal:

Year:

2015

Language:

english

File:

PDF, 1015 KB

english, 2015

22

Metabolome analyses in exposome studies: Profiling methods for a vast chemical space

Athersuch, Toby

Journal:

Archives of Biochemistry and Biophysics

Year:

2015

Language:

english

File:

PDF, 959 KB

english, 2015

23

Emergence of new properties in the investigation of disease aetiology: The contribution of omics

Athersuch, Toby James

Journal:

Toxicology Letters

Year:

2016

Language:

english

File:

PDF, 57 KB

english, 2016

24

Assessment of metabolic phenotypic variability in children’s urine using 1H NMR spectroscopy

Maitre, Léa, Lau, Chung-Ho E., Vizcaino, Esther, Robinson, Oliver, Casas, Maribel, Siskos, Alexandros P., Want, Elizabeth J., Athersuch, Toby, Slama, Remy, Vrijheid, Martine, Keun, Hector C., Coen, Mu

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

25

Oxidative stress and inflammation induced by environmental and psychological stressors: a biomarker perspective

Ghezzi, Pietro, Floridi, Luciano, Boraschi, Diana, Cuadrado, Antonio, Manda, Gina, Levic, Snezana, D'Acquisto, Fulvio, Hamilton, Alice Laura, Athersuch, Toby, Selley, Liza

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

26

Metabolic Hydrolysis of Aromatic Amides in Selected Rat, Minipig, and Human In Vitro Systems

Bradshaw, Peter R., Wilson, Ian D., Gill, Rachel Upcott, Butler, Philip J., Dilworth, Clive, Athersuch, Toby J.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.92 MB

english, 2018

27

Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective

Athersuch, Toby J., Antoine, Daniel J., Boobis, Alan R., Coen, Muireann, Daly, Ann K., Possamai, Lucia, Nicholson, Jeremy K., Wilson, Ian D.

Journal:

Toxicology Research

Year:

2018

Language:

english

File:

PDF, 4.53 MB

english, 2018

28

A multivariate approach to investigate the combined biological effects of multiple exposures

Jain, Pooja, Vineis, Paolo, Liquet, Benoît, Vlaanderen, Jelle, Bodinier, Barbara, van Veldhoven, Karin, Kogevinas, Manolis, Athersuch, Toby J, Font-Ribera, Laia, Villanueva, Cristina M, Vermeulen, Roe

Journal:

Journal of Epidemiology & Community Health

Year:

2018

Language:

english

File:

PDF, 2.33 MB

english, 2018

29

Yale school of public health symposium on lifetime exposures and human health: the exposome; summary and future reflections

Johnson, Caroline H., Athersuch, Toby J., Collman, Gwen W., Dhungana, Suraj, Grant, David F., Jones, Dean P., Patel, Chirag J., Vasiliou, Vasilis

Journal:

Year:

2017

Language:

english

File:

PDF, 362 KB

english, 2017

30

Automatic Sampling and Analysis of Organics and Biomolecules by Capillary Action-Supported Contactless Atmospheric Pressure Ionization Mass Spectrometry

Hsieh, Cheng-Huan, Meher, Anil Kumar, Chen, Yu-Chie, Athersuch, Toby James.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.23 MB

english, 2013

31

Metabonomic Evaluation of Chronic Unpredictable Mild Stress-Induced Changes in Rats by Intervention of Fluoxetine by HILIC-UHPLC/MS

Zhao, Longshan, Xiong, Zhili, Lu, Xiumei, Zheng, Shuning, Wang, Fang, Ge, Lin, Su, Guangyue, Yang, Jingyu, Wu, Chunfu, Athersuch, Toby James

Journal:

Year:

2015

Language:

english

File:

PDF, 976 KB

english, 2015

32

Determinants of the urinary and serum metabolome in children from six European populations

Lau, Chung-Ho E., Siskos, Alexandros P., Maitre, Léa, Robinson, Oliver, Athersuch, Toby J., Want, Elizabeth J., Urquiza, Jose, Casas, Maribel, Vafeiadi, Marina, Roumeliotaki, Theano, McEachan, Rosemar

Journal:

Year:

2018

Language:

english

File:

PDF, 3.07 MB

english, 2018

33

Brake dust exposure exacerbates inflammation and transiently compromises phagocytosis in macrophages

Selley, Liza, Schuster, Linda, Marbach, Helene, Forsthuber, Theresa, Forbes, Ben, Gant, Timothy W., Sandström, Thomas, Camiña, Nuria, Athersuch, Toby J., Mudway, Ian, Kumar, Abhinav

Journal:

Year:

2020

Language:

english

File:

PDF, 2.42 MB

english, 2020

34

Kinetic modelling of acyl glucuronide and glucoside reactivity and development of structureâproperty relationships

Bradshaw, Peter R., Richards, Selena E., Wilson, Ian D., Stachulski, Andrew V., Lindon, John C., Athersuch, Toby J.

Journal:

Organic & Biomolecular Chemistry

Year:

2020

File:

PDF, 2.02 MB

2020

35

Acyl glucuronide reactivity in perspective

Bradshaw, Peter R., Athersuch, Toby J., Stachulski, Andrew V., Wilson, Ian D.

Journal:

Drug Discovery Today

Year:

2020

File:

PDF, 2.14 MB

2020

36

Simultaneous Enantiospecific Detection of Multiple Compounds in Mixtures using NMR Spectroscopy

Kuhn, Lars T., Motiram-Corral, Kumar, Athersuch, Toby J., Parella, Teodor, PÃ©rez-Trujillo, MÃriam

Journal:

Angewandte Chemie International Edition

Year:

2020

File:

PDF, 921 KB

2020

37

Simultaneous Enantiospecific Detection of Multiple Compounds in Mixtures using NMR Spectroscopy

Kuhn, Lars T., Motiram-Corral, Kumar, Athersuch, Toby J., Parella, Teodor, PÃ©rez-Trujillo, MÃriam

Journal:

Angewandte Chemie

Year:

2020

File:

PDF, 921 KB

2020